Thermo Fisher Scientific NFRKB Polyclonal Antibody
NFRKB 단백질을 인식하는 Thermo Fisher Scientific의 다클론성 Rabbit IgG 항체입니다. Western blot과 Immunocytochemistry에 적합하며, 인체 및 설치류 등 다양한 종에 반응합니다. 고순도 친화 크로마토그래피로 정제되었으며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NFRKB (Accession Q6P4R8), corresponding to amino acid residues Q463–S513 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818598 |
Product Specific Information
Antibody detects endogenous levels of total NFRKB.
Target Information
NFRKB (nuclear factor related to kappa-B-binding protein) was first identified as a factor that could bind a variant NF-kappa B site in the interleukin-2 receptor alpha (IL-2R alpha) gene.
NFRKB appears to be a transcription factor central to immune cell development. Evidence of this comes from the identification of NFRKB as an amplified gene in several cases of acute myeloid leukemia.
Additionally, in another clinical case, a partial deletion of the chromosomal region that includes NFRKB is shown to be associated with combined cellular immunodeficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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