Thermo Fisher Scientific DCAF7 Polyclonal Antibody

Thermo Fisher Scientific DCAF7 Polyclonal Antibody

Applications

• Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:200

Product Specifications

Product Specific Information

This antibody detects endogenous levels of total DCAF7 protein.

Target Information

WD-repeats are motifs found in various proteins and are characterized by a conserved core of 40–60 amino acids that typically form a propeller-like tertiary structure. Proteins containing WD-repeats are involved in diverse cellular functions such as chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis, and vesicular trafficking.

WDR68 (WD repeat-containing protein 68), also known as DCAF7 (DDB1- and CUL4-associated factor 7), HAN11, or WDR68, is a 342-amino acid protein belonging to the WD repeat DCAF7 family and contains four WD repeats. It localizes to the cytoplasm and nucleus, participates in protein modification and ubiquitination pathways, and interacts directly with Dyrk1A, Dyrk1B, and Dia1. WDR68 is implicated in craniofacial and skin development.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.