Thermo Fisher Scientific WDR4 Polyclonal Antibody
WDR4 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 실험에 사용 가능. 높은 특이성과 항원 친화 크로마토그래피로 정제됨. Human 및 Mouse 반응성. 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein of human WDR4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636611 |
Product Specific Information
This antibody detects endogenous levels of total WDR4 protein.
Target Information
WDR4 is required for 7-methylguanosine modification of tRNA and belongs to the WD repeat protein family. WD repeats are conserved regions (~40 amino acids) typically bracketed by gly-his and trp-asp (GH-WD), facilitating formation of multiprotein complexes. Members of this family participate in cell cycle progression, signal transduction, apoptosis, and gene regulation.
WDR4 has been excluded as a candidate for nonsyndromic deafness (DFNB10) but remains a candidate for other disorders mapped to 21q22.3 and for Down syndrome phenotypes. Alternative splicing generates at least three transcript variants, two diverging at the 3′ UTR encoding identical protein products.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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