Thermo Fisher Scientific WSB1 Polyclonal Antibody
Thermo Fisher Scientific의 WSB1 Polyclonal Antibody는 인간 WSB1 단백질을 인식하는 토끼 유래 다클론 항체입니다. IHC(P)에서 1:100–1:200 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 버퍼(40% 글리세롤) 내 액상 형태로 -20°C 보관합니다.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein of human WSB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636618 |
Product Specific Information
This antibody detects endogenous levels of total WSB1 protein.
Target Information
WSB1 (WD repeat and SOCS box-containing 1), also known as SWIP1, is a 421 amino acid protein containing one SOCS box domain and six WD repeats. It is expressed as multiple alternatively spliced isoforms and functions as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins such as DIO2. Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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