Thermo Fisher Scientific TIMP4 Polyclonal Antibody
TIMP4 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western Blot 및 Immunohistochemistry(Paraffin)에서 검증됨. 고순도(>95%) 항체로, 항원 친화 크로마토그래피로 정제됨. 장기 보관 시 -20°C에서 안정적.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 172–220 of Human TIMP-4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803046 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
Tissue inhibitor of metalloproteinase 4 (TIMP4) is encoded by the gene TIMP4 located on chromosome 3. It belongs to the TIMP gene family and inhibits matrix metalloproteinases (MMPs), which degrade components of the extracellular matrix.
TIMP4 irreversibly binds to MMPs and inactivates them with zinc as a cofactor. The netrin domain of TIMP4 is involved in platelet recruitment and aggregation. Additional biological functions include:
- Response to cytokine and peptide hormone stimuli
- Involvement in ovulation cycle and CNS development
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-86257_TIMP4_Q99727-1_Rabbit.svg, PA5-86257_TIMP4_Q99727-1_Rabbit_PDP.jpeg)
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