Thermo Fisher Scientific alpha Internexin Monoclonal Antibody (1D2)
다양한 종(고양이, 인간, 생쥐, 랫드 등)에 반응하는 알파 인터넥신 단클론 항체. Western blot, IHC, ICC 등에서 사용 가능. 신경 발달 초기 단계의 뉴런 표지 연구에 적합. 장기 보관 시 -20°C 저장 권장. 연구용으로만 사용.
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- MA316752
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카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:5,000 |
| Immunohistochemistry - Free Floating (IHC (Free)) | Assay-Dependent |
| Immunocytochemistry (ICC/IF) | 1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cat, Human, Mammal, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D2 |
| Immunogen | Raised against purified recombinant rat alpha-internexin expressed in and purified from E. coli. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Purification | Affinity chromatography |
| Storage Buffer | Tissue culture supernatant/PBS with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_568592 |
Target Information
alpha-Internexin is a Class IV intermediate filament subunit expressed very early in neuronal development. It is related to but distinct from the better known neurofilament triplet proteins (NF-L, NF-M, NF-H), sharing similar sequence motifs and intron organization. Many mature neurons contain alpha-internexin in addition to NF-L, NF-M, and NF-H, while in some neurons it is the only neurofilament subunit expressed.
Antibodies to internexin serve as unique probes to study and classify neuronal types and trace neuronal processes in tissue sections and cultures. Due to its early developmental expression, alpha-internexin serves as an early diagnostic marker for neuronal progenitor cells and other neuron-committed cells. Although its use in brain tumor studies has not been fully explored, it presents potential interest for such research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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