Thermo Fisher Scientific NEFM Polyclonal Antibody
NEFM 단백질을 인식하는 염소 유래 polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간 및 생쥐 반응성. 0.5 mg/mL 농도의 액상 제형이며, 신경세포 마커 연구에 적합. 연구용으로만 사용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific NEFM Polyclonal Antibody
Thermo Fisher Scientific NEFM Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.03–0.1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QASHITVERKDYLK) corresponding to internal amino acids of NEFM (aa 250–263) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10983250 |
Product Specific Information
This antibody is predicted to react with bovine, canine, human, porcine, and rat based on sequence homology.
Tested in Peptide ELISA: antibody detection limit dilution 128,000.
Target Information
Neurofilaments (NFs) are intermediate filaments expressed almost exclusively in neuronal cells, prominently in large axons. NFs consist of three polypeptide chains—NF-M, NF-H, and NF-L—with structural similarity in the coiled-coil core domain but differing in terminal sequences. NF-M tail interactions are essential for axonal architecture and are regulated by phosphorylation and O-GlcNAcylation, affecting filament formation and function.
Antibodies against neurofilament subunits serve as useful neuronal markers due to their abundance, neuron-specific expression, and biochemical stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.