Thermo Fisher Scientific PSME1 Polyclonal Antibody
Thermo Fisher Scientific의 PSME1 Polyclonal Antibody는 인간 단백질에 반응하며, Western blot에 최적화된 goat polyclonal 항체입니다. 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 제공되고 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (KNFEKLKKPRGETK) corresponding to the C-terminus amino acids of PSME1 (aa 232–246) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10979726 |
Product Specific Information
- This antibody is predicted to react with canine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
Proteolytic degradation is essential for maintaining appropriate levels of short-lived and regulatory proteins involved in diverse cellular processes such as metabolism, stress response, antigen presentation, receptor modulation, cell cycle regulation, and transcriptional signaling.
The ubiquitin-proteasome pathway is responsible for degrading most cytosolic and nuclear proteins in eukaryotic cells. The 26S proteasome, an ATP-dependent multisubunit complex (~2.5 MDa), consists of a 20S proteolytic core and one or two 19S regulatory subunits. The 19S subunits recognize ubiquitinated proteins, unfold them, and translocate them into the 20S core for degradation.
Defects in the ubiquitin-proteasome pathway are linked to several genetic diseases, including cystic fibrosis, Angelman’s syndrome, and Liddle syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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