Thermo Fisher Scientific Kir6.2 (KCNJ11) Polyclonal Antibody
Kir6.2(KCNJ11) 단백질을 인식하는 염소 유래 폴리클로날 항체입니다. Western blot 및 IHC(P) 실험에 적합하며, 고순도 정제 및 안정적 저장 조건을 제공합니다. 인공 펩타이드 면역원 기반으로 제작되어 높은 특이성을 보장합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 3–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (AEDPAKPRYRARQ) corresponding to the internal amino acids of KCNJ11 (aa 18–23) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10982587 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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