Thermo Fisher Scientific IRF6 Polyclonal Antibody
IRF6 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot 및 ELISA에 적합하며, 세포질 및 핵에서 발현되는 IRF6 검출에 활용됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 115–300 of human IRF6 (NP_006138.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914551 |
Product Specific Information
- Positive test controls: 22Rv1, BT-474, HT-29, MCF7, 293T, Mouse liver, Mouse kidney, Rat liver
- Localization: Cytoplasm, Nucleus
Immunogen sequence:
DIPQPQGSII NPGSTGSAPW DEKDNDVDEE DEEDELDQSQ HHVPIQDTFP FLNINGSPMA PASVGNCSVG NCSPEAVWPK TEPLEMEVPQ APIQPFYSSP ELWISSLPMT DLDIKFQYRG KEYGQTMTVS NPQGCRLFYG DLGPMPDQEE LFGPVSLEQV KFPGPEHITN EKQKLFTSKL LDVMDR
Target Information
This gene encodes a member of the interferon regulatory transcription factor (IRF) family.
Family members share a highly conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain.
Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome.
This protein is involved in palate formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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