Thermo Fisher Scientific NMNAT1 Polyclonal Antibody
Human NMNAT1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 ELISA에 적합합니다. NAD 생합성 관련 연구에 활용 가능하며, 고순도의 Affinity 정제 항체입니다. PBS/glycerol buffer에 보존되며 -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein corresponding to amino acids 1–150 of human NMNAT1 (NP_0736242) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.72 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806636 |
Product Specific Information
Immunogen sequence:
MENSEKTEVV LLACGSFNPI TNMHLRLFEL AKDYMNGTGR YTVVKGIISP VGDAYKKKGL IPAYHRVIMA ELATKNSKWV EVDTWESLQK EWKETLKVLR HHQEKLEASD CDHQQNSPTL ERPGRKRKWT ETQDSSQKKS LEPKTKAVPKPositive Samples: Mouse liver, Mouse testis, Rat liver
Cellular Location: Nucleus
Target Information
The coenzyme NAD and its derivatives are involved in numerous metabolic redox reactions and participate in protein ADP-ribosylation, histone deacetylation, and Ca(2+) signaling pathways.
NMNAT (EC 2.7.7.1) acts as a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.
(Zhang et al., 2003 [PubMed 12574164]; supplied by OMIM)
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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