Thermo Fisher Scientific OSMR Polyclonal Antibody
Thermo Fisher Scientific의 OSMR Polyclonal Antibody는 인간 및 마우스 시료에 반응하며, Western blot과 ELISA에서 검증된 고품질 항체입니다. 재조합 단백질을 면역원으로 사용하여 제작되었으며, 액상 형태로 제공되고 -20°C에서 안정적으로 보관 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 100–200 of human OSMR (NP_003990.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.62 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806639 |
Product Specific Information
- Positive Samples: 293T, HeLa, HepG2, Raji, Mouse lung, Mouse heart
- Cellular Location: Membrane, Single-pass type I membrane protein
- Immunogen sequence:
ESELPLECAT HFVRIKSLVD DAKFPEPNFW SNWSSWEEVS VQDSTGQDIL FVFPKDKLVE EGTNVTICYV SRNIQNNVSC YLEGKQIHGE QLDPHVTAFN L
Target Information
Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells.
OSMR is an alternative subunit for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF.
Publication Note: This RefSeq record includes a subset of the publications available for this gene. Please see the Entrez Gene record to access additional publications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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