Thermo Fisher Scientific PPM1A Polyclonal Antibody
PPM1A 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF, ChIP, RIP 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성이 확인되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 1 mg/mL 농도의 액상 형태로 제공되며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
| ChIP assay (ChIP) | Assay-dependent | - |
| RNA Immunoprecipitation (RIP) | - | View 1 publication |
Product Specifications
| Category | Specification |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–264 of Human PPM1A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1 M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546751 |
Product Specific Information
- Recommended positive controls: 293T, A431, mouse brain, PC-12, Rat2
- Predicted reactivity: Mouse (99%), Rat (99%), Xenopus laevis (89%), Rabbit (99%), Bovine (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PPM1A (Protein phosphatase 1A), also known as PPPM1A, belongs to the PP2C family.
It is a serine/threonine protein phosphatase essential for regulating cellular stress responses in eukaryotes.
PPM1A plays a role in tumor suppression and negatively regulates multiple signaling pathways critical for trophoblast invasion.
This protein is distributed in both the cytoplasm and nucleus of mammalian cells and has two isoforms produced by alternative splicing.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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