
Thermo Fisher Scientific PISD Monoclonal Antibody (OTI2H1), TrueMAB
PISD 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western Blot에 적합합니다. Human 시료 반응성이 있으며, Mouse IgG2a 아이소타입입니다. 동결건조 형태로 제공되며, 고순도의 친화 크로마토그래피 정제 제품입니다.
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Applications
- Western Blot (WB): 1:200–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 80–340 of human PISD produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to reach a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882) to ensure carrier-free conditions.
Target Information
Phosphatidylserine decarboxylases (PSDs) catalyze the formation of phosphatidylethanolamine (PE) by decarboxylation of phosphatidylserine (PS).
Type I PSDs, such as PISD, are targeted to the inner mitochondrial membrane via an N-terminal targeting sequence.
PISD contains a conserved LGST motif functioning as an autocatalytic cleavage site, splitting the proenzyme into mature alpha and beta subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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