Thermo Fisher Scientific SOD2 (MnSOD) Polyclonal Antibody
SOD2(MnSOD)에 특이적인 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 동결건조 제형. -20°C 보관, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL | – |
| Immunocytochemistry (ICC/IF) | 0.5–1 µg/mL | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human SOD2 (45–62aa QIMQLHHSKHHAAYVNNL) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2747163 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS).
SOD catalyzes the dismutation of superoxide radical anion (O₂⁻) to hydrogen peroxide, which is subsequently converted to water and oxygen by glutathione peroxidase and catalase.
Several classes of SOD have been identified:
- SOD1 (Cu, Zn-SOD): Intracellular, homodimeric enzyme (32 kDa) containing Cu and Zn ions per subunit.
- SOD2 (Mn-SOD): Mitochondrial, tetrameric enzyme (80 kDa) containing manganese, located in the mitochondrial matrix near the respiratory chain.
- SOD3 (EC-SOD): Extracellular, heparin-binding multimer expressed in lungs, vessel walls, and airways.
- SOD4 (CCS): Copper chaperone that delivers Cu to SOD1, aiding in its activation.
⚠ WARNING:
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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