Thermo Fisher Scientific STAT5 alpha/beta Recombinant Rabbit Monoclonal Antibody (ARC1215)
STAT5 alpha/beta 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며 HEK293 세포에서 발현되었습니다. 고순도 친화 크로마토그래피로 정제된 액상 항체로, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1215 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 600–786 of human STAT5 (P42229) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849525 |
Product Specific Information
Immunogen sequence:
KQQAHDLLIN KPDGTFLLRF SDSEIGGITI AWKFDSPERN LWNLKPFTTR DFSIRSLADR LGDLSYLIYV FPDRPKDEVF SKYYTPVLAK AVDGYVKPQI KQVVPEFVNA SADAGGSSAT YMDQAPSPAV CPQAPYNMYP QNPDHVLDQD GEFDLDETMD VARHVEELLR RPMDSLDSRL SPPAGLF
Target Information
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by receptor-associated kinases and then form homo- or heterodimers that translocate to the cell nucleus, acting as transcription activators. This protein mediates responses to ligands such as IL-2, IL-3, IL-7, GM-CSF, erythropoietin, thrombopoietin, and various growth hormones. Its activation in myeloma and lymphoma with TEL/JAK2 fusion is independent of cell stimulus and is essential for tumorigenesis. The mouse counterpart induces expression of BCL2L1/BCL-X(L), suggesting an antiapoptotic function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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