Thermo Fisher Scientific MUSK Polyclonal Antibody
Thermo Fisher Scientific의 MUSK Polyclonal Antibody는 인간 MUSK 단백질을 인식하는 토끼 유래 IgG 항체로, WB, IHC, Flow Cytometry에 적합합니다. 액상 형태이며 1.3 mg/mL 농도로 제공되며, 근육 발달 및 신경근 접합 연구에 활용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 35–65 amino acids from the N-terminal region of human MUSK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2250951 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
MUSK plays an important and selective role in skeletal muscle development and function, particularly in postsynaptic differentiation and formation of end-plate bands in cooperation with Rapsyn. It is part of the agrin signaling complex and contributes to the development and architectural maintenance of the neuromuscular junction. Receptor tyrosine kinase activity is regulated by ligand binding to the extracellular active site.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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