Thermo Fisher Scientific SNAI2 Monoclonal Antibody (OTI2C3), TrueMAB
SNAI2 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 Flow cytometry에 적합합니다. 인간 시료에 반응하며, 동결건조 형태로 제공됩니다. 재구성 및 결합 실험에 용이하며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C3 |
| Immunogen | Full length human recombinant protein of human SNAI2 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Slug (SNAI2) is a member of the Snail family of C2H2-type zinc finger transcription factors, involved in epithelial-mesenchymal transitions and neural tube formation during vertebrate embryogenesis.
It can be induced by growth factors such as FGF, BMP, and TGF-beta. Slug binds E-box regions of promoters and represses transcription of genes such as E-cadherin and Claudin-1.
Its expression in several carcinomas (breast, esophageal, colorectal) correlates with poor prognosis. Slug also protects hemopoietic progenitor cells from radiation-induced apoptosis by repressing p53-mediated transcription of Puma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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