Thermo Fisher Scientific Cardiac Actin Monoclonal Antibody (AC1-20.4.2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (IHC)

1:10

-

Immunohistochemistry (Paraffin) (IHC (P))

1:10

-

Product Specifications

Species Reactivity

Bovine, Chicken, Human, Mouse, Rabbit

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

AC1-20.4.2

Immunogen

Synthetic NH2 terminus decapeptide of cardiac isoform of actin if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:alpha-Cardiac Actin,uniProtId:P68033-1,ncbiNodeId:10090,antigenRange:1,antigenLength:377,antigenImageFileName:690075-1ML_alpha-Cardiac_Actin_P68033-1_House_mouse.svg,antigenImageFileNamePDP:690075-1ML_alpha-Cardiac_Actin_P68033-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 0.5% BSA

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

ACTC1 are part of actins, which are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.