Thermo Fisher Scientific IL-18 (Interleukin-6)/Interferon beta-2 (Hybridoma Growth Factor) Monoclonal Antibody (IL18/4626)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL

-

Peptide Array (Array)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2, kappa

Class

Monoclonal

Type

Antibody

Clone

IL18/4626

Immunogen

Recombinant fragment (around aa1-193) of human IL-18 protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IL-18,uniProtId:Q14116-1,ncbiNodeId:9606,antigenRange:1-193,antigenLength:193,antigenImageFileName:3606-MSM6-P0_IL-18_Q14116-1_House_mouse.svg,antigenImageFileNamePDP:3606-MSM6-P0_IL-18_Q14116-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive Control:Human heart or adrenal gland. Stimulated peritoneal macrophages.

Cellular Location: Secreted.

Target Information

The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein can specifically interact with this cytokine, and thus negatively regulate its biological activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.