Thermo Fisher Scientific RRM1 Monoclonal Antibody (OTI6G8), TrueMAB
RRM1 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI6G8). Western blot 및 IHC(P) 검증 완료. Human 시료 반응성. 동결건조 형태로 제공되며, PBS buffer와 trehalose 포함. 연구용으로 DNA 합성 관련 효소 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6G8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 541–792 of human RRM1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
- For conjugation experiments, an additional desalting step is recommended (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
RRM1 (Ribonucleotide reductase M1 polypeptide) is one of two non-identical subunits of ribonucleoside-diphosphate reductase, an enzyme catalyzing the biosynthesis of deoxyribonucleotides from ribonucleotides. It provides essential precursors for DNA synthesis and is implicated in carcinogenesis and tumor progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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