Thermo Fisher Scientific TBLR1 Monoclonal Antibody (OTI2A8)
TBLR1 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 적합. 인간, 마우스, 랫트 반응성. 고순도 Affinity Chromatography 정제, 1 mg/mL 농도. PBS/BSA/glycerol buffer에 보관하며 -20°C에서 안정적 저장 가능.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A8 |
| Immunogen | Full length human recombinant protein of TBL1XR1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725482 |
Target Information
Chromatin organization plays a fundamental role in regulating transcription in eukaryotic cells. The nuclear receptor corepressor (N-CoR) and silencing mediator of retinoid and thyroid hormone receptors (SMRT) are involved in transcriptional repression pathways. These complexes recruit histone deacetylases (HDACs), particularly HDAC3, to form repressive chromatin. TBLR1, a WD-40 repeat protein, associates with N-CoR and SMRT complexes and is considered a core component, though its exact role remains to be elucidated.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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