Thermo Fisher Scientific RNF12 Monoclonal Antibody (OTI2D7)
RNF12 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI2D7). Western blot 및 IHC(P) 검증 완료. Human 시료에 반응하며, 1 mg/mL 농도의 액상 형태로 제공. PBS buffer에 BSA, glycerol 포함, -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D7 |
| Immunogen | Full length human recombinant protein of RLIM produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725248 |
Target Information
RNF12 is a RING-H2 zinc finger protein functioning as a ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), leading to proteasome-dependent degradation of LDB1. RNF12 and LDB1 act as co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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