Thermo Fisher Scientific NYREN18 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human NYREN18 protein. Validated for WB and ICC/IF. Supplied as liquid, unconjugated form with 0.14 mg/mL concentration. Suitable for research use in studying NEDD8 conjugation pathways.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 358–615 of Human NYREN18 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.14 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545032 |
Product Specific Information
- Recommended positive control: A549 cells
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
NYREN18 is a specific down-regulator of the NEDD8 conjugation system.
It recruits NEDD8 and its conjugates to the proteasome for degradation and interacts with PSMD4/S5a, a member of the regulatory subunit of the 26S proteasome.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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