Thermo Fisher Scientific Nrf2 Recombinant Rabbit Monoclonal Antibody (2D12)
Nrf2 단백질을 검출하기 위한 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. 인간 시료에 반응하며 ICC/IF 및 ELISA에 사용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로만 사용.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:20–1:200
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2D12 |
| Immunogen | A synthesized peptide derived from human Nrf2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092648 |
Target Information
Nfr1 (also designated TCF11), Nrf2, and Nfr3 are bZIP transcription factors that heterodimerize with Maf proteins to bind MARE (Maf recognition elements) sequences.
Nrf2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from a repressor protein, Keap1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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