Thermo Fisher Scientific DYNLL1 Recombinant Rabbit Monoclonal Antibody (SD08-04)
DYNLL1 단백질을 표적하는 재조합 토끼 단클론 항체로, 높은 특이성과 민감도를 제공. Western blot, IHC, ICC/IF에 적합하며, 일관된 로트 품질과 동물 유래 성분이 없는 제형. 연구용으로 세포 내 수송 및 신경 산화질소 합성 조절 관련 연구에 활용 가능.
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Thermo Fisher Scientific DYNLL1 Recombinant Rabbit Monoclonal Antibody (SD08-04)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SD08-04 |
| Immunogen | Synthetic peptide within Human DYNLL1 aa 1–50 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% Sodium Azide |
| Storage Conditions | Store at 4°C short term; for long-term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2809664 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages include:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
Cytoplasmic dyneins are large enzyme complexes (~1,200 kD) containing two force-producing heads formed from dynein heavy chains and stalks linking them to a basal domain with accessory intermediate chains.
DYNLL1 is a light chain component of this complex and interacts with neuronal nitric oxide synthase (nNOS), inhibiting its activity by destabilizing the nNOS dimer. This regulation may influence various biological processes through nitric oxide synthase activity modulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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