Thermo Fisher Scientific HNF1-alpha Polyclonal Antibody
HNF1-alpha 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, IP 등에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태. 인체 시료에 반응하며, 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 50 to 100 of human HNF1 Homeobox A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting potential use in specific immunotherapy for cancer. It is also a member of the NELF (negative elongation factor) complex involved in RNA polymerase II transcription elongation regulation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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