Thermo Fisher Scientific PD-L1 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1141)
PD-L1 단백질을 특이적으로 인식하는 알파카 유래 재조합 단클론 항체. ELISA 분석에 적합하며 CHO 세포에서 발현된 VHH 형태. Metal-chelate chromatography로 정제된 고순도 액상 제품. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific PD-L1 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1141)
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1141 |
| Immunogen | Recombinant Human CD274/PD-L1/B7-H1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. PD-L1 binds to its receptor, programmed death receptor 1 (PD-1), which negatively regulates T-cell receptor (TCR) signaling. Upon ligation, PD-L1 decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in many murine and human cancers and can be up-regulated by IFN-gamma stimulation. Therefore, PD-L1 may play a crucial role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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