Thermo Fisher Scientific c-Fos Polyclonal Antibody
c-Fos 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. 면역조직화학(IHC, IHC-F) 적용 가능. Sheep/IgG 호스트 기반, 단백질 G 정제, PBS 버퍼에 동결건조 형태로 제공. 세포 신호전달 및 전사 조절 연구에 적합.
- 카탈로그번호
- PA118329
- 판매단위
- pk
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Thermo Fisher Scientific c-Fos Polyclonal Antibody
Applications
Immunohistochemistry (IHC)
Tested Dilution: -
View 2 publicationsImmunohistochemistry (Frozen) (IHC (F))
Tested Dilution: 10 µg/mL
View publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rabbit, Rat |
| Published Species | Rat |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminal residues M(2) F S G F N A D Y E A S S S R C(17) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1073602 |
Product Specific Information
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
After reconstitution, keep aliquots at -20°C for higher stability, and at 4°C with an appropriate antibacterial agent.
Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
Target Information
FBJ murine osteosarcoma viral oncogene homolog, commonly known as Cellular protooncogene Fos (c-Fos), belongs to the fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14.
c-Fos heterodimerizes with c-Jun to form the Activator Protein-1 (AP-1) transcription factor, which regulates transcription of several genes involved in cellular signal transduction, cell proliferation, and differentiation.
c-Fos is phosphorylated by various stimuli including growth factors and insulin at multiple sites. The upstream kinase for phosphorylation at Threonine 232 is ERK MAPK, which regulates localization of c-Fos to the nucleus and is critical for c-Fos-induced transcriptional activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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