Thermo Fisher Scientific GLT-1 Polyclonal Antibody
GLT-1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, ICC/IF, ELISA에 사용 가능. Human 및 Mouse 시료 반응성. Affinity Chromatography로 정제된 액상 항체이며, PBS/glycerol buffer에 보관. 신경세포 글루타메이트 수송체 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 474–574 of human EAAT2/SLC1A2 (NP_0041622) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.18 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804222 |
Product Specific Information
- Positive Samples: MCF7, HepG2, SW480, Mouse liver, Rat liver
- Cellular Location: Membrane, Multi-pass membrane protein
- Immunogen sequence:
LDRMRTSVNV VGDSFGAGIV YHLSKSELDT IDSQHRVHED IEMTKTQSIY DDMKNHRESN SNQCVYAAHN SVIVDECKVT LAANGKSADC SVEEEPWKRE K
Target Information
Excitatory amino acid transporter 2 (EAAT2) is a member of a family of solute transporter proteins. This membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is essential for proper synaptic activation and for preventing neuronal damage due to excessive activation of glutamate receptors. Mutations or decreased expression of this protein are associated with amyotrophic lateral sclerosis (ALS). Alternatively spliced transcript variants of this gene have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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