Thermo Fisher Scientific RSV Fusion Protein Recombinant Rabbit Monoclonal Antibody (R338)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

-

Neutralization (Neu)

0.6-2.3 µg/mL

-

Product Specifications

Species Reactivity

Virus

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

R338

Immunogen

Recombinant Human respiratory syncytial virus (RSV) Fusion glycoprotein/RSV-F protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

6.13 mg/mL

Purification

Protein A

Storage buffer

histidine/arginine, pH 6.0, with 120mM NaCl, 0.02% Tween 80

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2912258

Product Specific Information

Specificity: Human respiratory syncytial virus (RSV) Fusion glycoprotein/RSV-F

Target Information

Human respiratory syncytial virus (RSV) is a member of the Paramyxoviridae family, subfamily Pneumovirinae, that causes common respiratory tract infections such as measles and mumps. Its genome consists of single stranded, negative sense RNA that encodes three envelope glycoproteins, a small hydrophobic (SH) protein of unknown function, a major glycoprotein (G) known as the attachment protein, and a fusion (F) protein. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, resulting in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells. Its name comes from the fact that F proteins on the surface of the virus cause the membranes on nearby cells to merge, forming syncytia. While RSV typically produces mild symptoms in adults, it is one of the leading causes of lower respiratory tract infections and hospital visits during infancy and childhood.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.