Thermo Fisher Scientific Phospho-KIF1C (Ser1092) Polyclonal Antibody
KIF1C 단백질의 Ser1092 인산화 형태를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot에 적합하며, 인간, 마우스, 랫트에 반응. 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
Species Reactivity
Human, Mouse, Rat
Antibody Information
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2662144 |
Immunogen
A synthesized peptide derived from human Kinesin-like Protein KIF1C (Phospho-Ser1092).
Target Family: KIF1C
UniProt ID: O43896-1
Antigen Range: 1081–1103
Antigen Length: 1103
Product Specific Information
Phospho-KIF1C (Ser1092) Polyclonal Antibody detects endogenous levels of KIF1C only when phosphorylated at Ser1092.
Target Information
Kinesins are microtubule-dependent motor proteins responsible for distributing organelles, vesicles, and macromolecular complexes throughout the cell. KIF1C, a member of the KIF1/Unc104 family, is involved in the transport of mitochondria or synaptic vesicles in axons.
Human KIF1C maps to chromosome 17p13 and encodes a 1,103 amino acid protein highly expressed in heart and skeletal muscle. Tyrosine phosphorylation regulates KIF1C-mediated retrograde transport of Golgi vesicles to the endoplasmic reticulum. KIF1C forms homodimers and associates with 14-3-3 beta, gamma, epsilon, and zeta. In mouse macrophages, KIF1C is required for anthrax lethal toxin resistance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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