Thermo Fisher Scientific CNGA1 Polyclonal Antibody
CNGA1 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 사용 가능하며, 시료는 Lyophilized 형태로 제공. 광수용체 탈분극 관련 연구 및 망막 질환 연구에 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to amino acid residues 41–54 of rat CNGA1 (Intracellular, N-terminus) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2857290 |
Product Specific Information
Reconstitute antibody with 50 µL of double distilled water (DDW).
The reconstituted solution can be stored at 4°C for up to 1 week.
For longer storage, aliquot and store at -20°C. Avoid multiple freeze-thaw cycles.
Centrifuge antibody preparations before use (10,000 × g, 5 min).
Peptide sequence: (C)NDNGSLSEESENED
Homology: Mouse – 13/14 amino acid residues identical; Human – 9/14 amino acid residues identical.
Target Information
The CNGA1 protein is involved in phototransduction. Together with another protein, it forms a cGMP-gated cation channel in the plasma membrane, enabling depolarization of rod photoreceptors — the final step in the phototransduction pathway.
Defects in CNGA1 are associated with autosomal recessive retinitis pigmentosa (ARRP).
Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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