Thermo Fisher Scientific Periostin (POSTN) Monoclonal Antibody (POSTN/3502)
인간 Periostin(POSTN)을 인식하는 마우스 단클론 항체로, IHC, ELISA, Peptide Array에 사용 가능. Protein A/G로 정제된 액상 항체이며, PBS(pH 7.4, 0.05% BSA) 버퍼에 보관. 4°C 보관, 동결 금지. 연구용 전용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| ELISA | Assay-dependent | - |
| Peptide Array | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | POSTN/3502 |
| Immunogen | Recombinant fragment (around aa193–326) of human POSTN protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Periostin (PN), also known as osteoblast-specific factor 2 (OSF-2), is a disulfide-linked, secreted protein that binds heparin and acts as a ligand for αVβ3 and αVβ5 integrins. In preosteoblasts, Periostin functions as a cell adhesion molecule involved in osteoblast recruitment, spreading, and attachment. It is mainly expressed in the lower gastrointestinal tract, aorta, stomach, placenta, uterus, and breast tissues, but is upregulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression is induced by BMP2 and TGF-β1. The protein contains a signal sequence, a cysteine-rich domain, four fasciclin-like repeats, and a C-terminal domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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