Thermo Fisher Scientific ATR Recombinant Rabbit Monoclonal Antibody (4O3E0)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

4O3E0

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 2100-2200 of human ATR. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ATR,uniProtId:Q13535-1,ncbiNodeId:9606,antigenRange:2100-2200,antigenLength:2644,antigenImageFileName:MA5-55249_ATR_Q13535-1_Rabbit.svg,antigenImageFileNamePDP:MA5-55249_ATR_Q13535-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

Immunogen Sequence: KAYEWEKAGR SDRVQMRNDL GKINKVITEH TNYLAPYQFL TAFSQLISRI CHSHDEVFVV LMEIIAKVFL AYPQQAMWMM TAVSKSSYPM RVNRCKEILN K

Target Information

The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.