Thermo Fisher Scientific ZNF638/NP220 Polyclonal Antibody
ZNF638/NP220 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 사용 가능. 인간 및 마우스 시료에서 반응 예측. 4°C 보관, 액상 형태.
- 카탈로그번호
- A301547Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ZNF638/NP220 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 225 and 275 of Human zinc finger protein 638 (Nuclear protein 220) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
Zinc-finger proteins contain DNA-binding domains and are involved in transcriptional activation or repression. NP220 (Nuclear protein 220), also known as Zinc finger protein 638 (ZNF638) or Cutaneous T-cell lymphoma-associated antigen se33-1, is a 1978 amino acid protein with one matrin-type zinc finger and two RNA recognition motif (RRM) domains, suggesting a role in transcriptional regulation. NP220 binds double-stranded DNA by recognizing cytidine clusters, interacts with FHL-2, and is phosphorylated by ATM or ATR upon DNA damage. It exists as five isoforms due to alternative splicing. Isoform five is a tumor-associated antigen found in cutaneous T-cell lymphoma (CTCL), including mycosis fungoides and Sezary syndrome patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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