Thermo Fisher Scientific ZNF638/NP220 Polyclonal Antibody
ZNF638(NP220) 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 Immunoprecipitation에 사용 가능. Human에 반응하며, 항원 친화 크로마토그래피로 정제됨. 4°C에서 보관하며 연구용으로만 사용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ZNF638/NP220 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 225 and 275 of Human zinc finger protein 638 (Nuclear protein 220) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
Zinc-finger proteins contain DNA-binding domains and have diverse functions, primarily involving transcriptional activation or repression.
NP220 (Nuclear protein 220), also known as Zinc finger protein 638 (ZNF638) or Cutaneous T-cell lymphoma-associated antigen se33-1, is a 1978 amino acid protein containing one matrin-type zinc finger and two RNA recognition motif (RRM) domains, suggesting a role in transcriptional regulation.
NP220 binds to double-stranded DNA fragments by recognizing clusters of cytidines and interacts with FHL-2. It is thought to be phosphorylated by ATM or ATR upon DNA damage.
Five isoforms exist due to alternative splicing. Isoform five of NP220 is a tumor-associated antigen found in several cutaneous T-cell lymphomas (CTCL), including mycosis fungoides and Sezary syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.