Thermo Fisher Scientific ACTN4 Monoclonal Antibody (4D10)
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ACTN4 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 4D10). Western blot 및 ELISA에 적합하며, Human, Mouse, Rat 시료에 반응. 액상 형태로 제공되며, -20°C에서 보관 권장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Concentration: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4D10 |
| Immunogen | ACTN4 (NP_004915, 592 a.a. ~ 701 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
KEAQRIAESN HIKLSGSNPY TTVTPQIINS KWEKVQQLVP KRDHALLEEQ
SKQQSNEHLR RQFASQANVV GPWIQTKMEE IGRISIEMNG TLEDQLSHLK QYERSIVDYKTarget Information
Alpha actinins belong to the spectrin gene superfamily, which includes alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles across cell types.
- In nonmuscle cells: localized along microfilament bundles and adherens-type junctions, linking actin to the membrane.
- In muscle cells: localized to Z-disc and dense bodies, anchoring myofibrillar actin filaments.
This gene encodes a nonmuscle alpha actinin isoform concentrated in the cytoplasm and implicated in metastatic processes. Mutations are associated with focal and segmental glomerulosclerosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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