Thermo Fisher Scientific NGAL Monoclonal Antibody (28)

Applications

Western Blot (WB)

• Assay-dependent

Immunohistochemistry (Paraffin) (IHC (P))

• 1:1,000

ELISA

• Assay-dependent

Product Specifications

Product Specific Information

ABS 048-28-02 binds free porcine NGAL in solution.
This antibody does not cross-react with human, dog, mouse, or rat.
ABS 048-28-02 can be used as a capture antibody in a sandwich ELISA using biotinylated detection antibody ABS 048-17-02.

Note: Concentration is lot-dependent and can vary from 0.85–1.15 mg/mL.

Target Information

NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin, and neutrophil lipocalin) is a 25 kDa glycosylated single-chain monomer and member of the lipocalin family of proteins that bind and transport small lipophilic molecules.
NGAL is released by activated neutrophils, can form dimers and small amounts of higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B).
Low-level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers.
Expression of NGAL in the kidney is dramatically increased by ischemic or nephrotoxic kidney injury.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.