Thermo Fisher Scientific ATP7B Monoclonal Antibody (L62/29), PE
ATP7B 단백질을 인식하는 PE 결합 단클론 항체로, 인간, 마우스, 랫트 시료에 반응합니다. Western blot, IHC, ICC/IF, IP 등에 사용 가능하며, 단백질 G로 정제된 액상 형태입니다. 4°C 보관, 형광 특성은 565/576 nm입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | L62/29 |
| Immunogen | Synthetic peptide amino acids 3–21 (cytoplasmic N-terminus) of human Copper-transporting ATPase2 |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931979 |
Available Formats
- Unconjugated (Cat. MA5-27719)
- APC (Cat. MA5-45522)
- FITC (Cat. MA5-45523)
- PerCP (Cat. MA5-45524)
- Custom conjugation available upon request
Product Specific Information
- 1 µg/mL of MA5-45525 detects Copper-transporting ATPase2 in 20 µg of rat brain lysate by colorimetric immunoblot using Goat IgG:HRP as secondary antibody.
- Detects approximately 160 kDa in rat brain membrane preparations.
- This antibody was formerly sold as clone S62-29.
Target Information
The ATP7B gene encodes a member of the P-type cation transport ATPase family, containing multiple membrane-spanning domains, an ATPase consensus sequence, hinge domain, phosphorylation site, and copper-binding sites.
This protein exports copper from cells, including hepatic copper efflux into bile.
Alternate splice variants with distinct localizations exist.
Mutations in ATP7B are associated with Wilson disease (WD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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