Thermo Fisher Scientific p75 NGF Receptor (NGFR) Monoclonal Antibody (OTI12E11)
인간, 마우스, 랫트 시료에 반응하는 p75 NGF 수용체 단일클론 항체. Western blot 및 유세포분석에 적합. 동결건조 형태로 공급되며 재구성 후 1 mg/mL 농도. 신경세포 발달 및 NGF 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12E11 |
| Immunogen | Full length human recombinant protein of human Ngfr (NP_002498) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to reach a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Neurotrophic factors regulate the survival, differentiation, and maintenance of neurons in both peripheral and central nervous systems, as well as other neural crest-derived cell types.
Developing sympathetic neurons depend on nerve growth factor (NGF) during target competition in vivo.
Antibodies specific to NGFR p75 are valuable tools for detecting and characterizing NGFR p75, aiding research into neuronal development, plasticity, and repair mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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