Thermo Fisher Scientific Importin 4 Polyclonal Antibody
Human Importin 4 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific Importin 4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to residues near the C-terminal of human Importin 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635886 |
Product Specific Information
The antibody detects endogenous levels of total IPO4 protein.
Target Information
Importin-4 is a protein encoded by the IPO4 gene in humans.
It functions as a nuclear transport receptor, mediating the import of proteins into the nucleus.
Importin-4 serves as a receptor for nuclear localization signals (NLS) in cargo substrates and facilitates docking of the importin/substrate complex to the nuclear pore complex (NPC).
Transport through the pore requires energy and is Ran-dependent.
At the nucleoplasmic side of the NPC, Ran binding leads to dissociation of the complex, and importin is re-exported to the cytoplasm where GTP hydrolysis releases Ran.
Usage Note
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지: PA5-50433_Importin_4_Q8TEX9-1_Rabbit.svg)
(이미지: PA5-50433_Importin_4_Q8TEX9-1_Rabbit_PDP.jpeg)
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