Thermo Fisher Scientific ZDHHC18 Polyclonal Antibody
ZDHHC18 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human, Mouse, Rat 시료에서 반응하며, Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ZDHHC18 (Accession Q9NUE0), corresponding to amino acid residues A42–G92 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853328 |
Product Specific Information
This antibody detects endogenous levels of total ZDHHC18.
Target Information
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, including transcriptional activation and repression.
ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger.
Expressed in fetal heart, lung, and kidney, and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase catalyzing the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA.
Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7, and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP25, and GABAA receptor proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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