Thermo Fisher Scientific CD263 (TRAIL-R3) Monoclonal Antibody (TRAIL-R3-02), PE
인간 TRAIL-R3(CD263)를 인식하는 단클론 항체로, Flow Cytometry에 적합합니다. PE 형광 표지로 565/576 nm의 Excitation/Emission 특성을 가집니다. 액상 형태로 4°C 암소 보관하며, TRAIL 유도 세포사멸 연구에 활용됩니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1–6 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TRAIL-R3-02 |
| Immunogen | TRAIL-R3-hIgGhc fusion protein |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152319 |
Additional Formats
Product Specific Information
This antibody reacts with TRAIL-R3, a 35 kDa GPI-anchored extracellular membrane protein expressed mainly on neutrophils.
Target Information
TRAIL-R3 (CD263) is a member of the TNF-receptor superfamily. It contains an extracellular TRAIL-binding domain and a transmembrane domain but lacks a cytoplasmic death domain. Consequently, it does not induce apoptosis and functions as an antagonistic receptor that protects cells from TRAIL-induced apoptosis.
This gene is p53-regulated and DNA damage-inducible. Expression is found in many normal tissues but not in most cancer cell lines, which may explain the sensitivity of cancer cells to TRAIL-induced apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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