Thermo Fisher Scientific PIT1 Polyclonal Antibody
Thermo Fisher Scientific PIT1 Polyclonal Antibody는 인간 POU1F1의 합성 펩타이드 영역을 면역원으로 한 Rabbit IgG 폴리클로날 항체입니다. Western blot과 IHC(P)에서 사용 가능하며 다양한 종에 높은 반응성을 보입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–2.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide region of human POU1F1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2166783 |
Product Specific Information
- Recommended positive control: HepG2
- Predicted reactivity: Cow (100%), Dog (100%), Goat (100%), Guinea Pig (100%), Horse (100%), Mouse (100%), Rabbit (100%), Rat (100%), Sheep (100%), Zebrafish (86%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals. It belongs to the POU family of transcription factors that regulate mammalian development. The family name derives from the first three members identified: PIT1 and OCT1 in mammals, and Unc-86 in C. elegans.
PIT1 contains two protein domains, POU-specific and POU-homeo, both essential for high-affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 also regulates genes encoding prolactin and thyroid-stimulating hormone beta subunit via thyrotropin-releasing hormone and cyclic AMP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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