Thermo Fisher Scientific PRMT5 Recombinant Superclonal Antibody (3HCLC)
인간 PRMT5 단백질을 인식하는 재조합 Superclonal 항체로, 높은 특이성과 민감도를 제공합니다. ICC/IF 및 ChIP 등 다양한 응용에 적합하며, 재현성 높은 결과를 제공합니다. 단기간 4°C, 장기간 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:100 |
| ChIP assay (ChIP) | 2 µg/million cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 3HCLC |
| Immunogen | Protein corresponding to human PRMT5 [aa1–aa291] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2784619 |
Product Specific Information
This antibody is predicted to react with Monkey, Cat, and Dog.
Recombinant rabbit Superclonal™ antibodies from Thermo Fisher Scientific combine multiple different recombinant monoclonal antibodies. These antibodies provide the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies. Each lot can be reproduced with the same known mixture of light and heavy chains, minimizing biological variability.
Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.
Target Information
PRMT5 (protein arginine N-methyltransferase 5) is an arginine methyltransferase that catalyzes the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), preferring MMA formation.
PRMT5 mediates symmetrical dimethylation of arginine residues in small nuclear ribonucleoproteins Sm D1 and Sm D3, which is essential for snRNP core particle assembly and biogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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