
Thermo Fisher Scientific PINK1 Recombinant Polyclonal Antibody (15HCLC)
인간 PINK1 단백질에 특이적인 재조합 Superclonal 토끼 항체입니다. 단일클론의 특이성과 다클론의 민감도를 결합하였으며, 높은 재현성과 일관성을 제공합니다. 면역세포염색(ICC/IF)에 적합하며, 단백질 A로 정제된 액상 항체입니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 15HCLC |
| Immunogen | Peptide corresponding to human PINK1 [aa292–aa310] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2848250 |
Product Specific Information
This antibody is predicted to react with Mouse, Rat, and Bovine.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine multiple different recombinant monoclonal antibodies, providing both the sensitivity of polyclonal antibodies and the specificity of monoclonal antibodies, with the consistency of recombinant production.
While functionally similar to polyclonal antibodies—recognizing multiple epitope sites on the target and offering higher detection sensitivity for low-abundance targets—a recombinant rabbit Superclonal™ antibody has a defined mixture of light and heavy chains that can be reproduced in every lot, eliminating biological variability.
Note: Formerly called “Recombinant Polyclonal Antibody,” now rebranded as “Recombinant Superclonal™ Antibody.” The product and performance remain unchanged.
Target Information
PINK1 (PTEN-induced putative kinase 1) protects cells from mitochondrial dysfunction by regulating autophosphorylation activity of mitochondrial genes. The kinase domain of PINK1 is essential for its protective role.
Mitochondrial proteins regulate cellular energy and stress adaptation, particularly in brain cells with high energy demands. Disruption of mitochondrial structure or function in the brain is linked to neurodegenerative diseases such as Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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