Thermo Fisher Scientific Androgen Receptor Recombinant Rabbit Monoclonal Antibody (5G7)
Thermo Fisher Scientific의 Androgen Receptor Recombinant Rabbit Monoclonal Antibody (5G7)는 인간 및 마우스 시료에서 AR 단백질 검출에 최적화된 항체입니다. Western blot, IHC, ICC/IF에 사용 가능하며, 고순도 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5G7 |
| Immunogen | A synthesized peptide derived from human Androgen Receptor (UniProt ID: P10275-1, antigen range: 1–22) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS (pH 7.4) with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898232 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
The androgen receptor (AR) is a member of the steroid-hormone receptor superfamily of nuclear receptors. It is a ligand-activated transcription factor that binds testosterone (T) and dihydrotestosterone (DHT). Upon ligand binding, AR translocates to the nucleus, dimerizes, and activates transcription of androgen-responsive genes. AR signaling is crucial for the development and function of male reproductive organs such as the prostate and epididymis, and also influences nonreproductive tissues including muscle, hair follicles, and brain. Abnormalities in AR signaling are associated with diseases such as prostate cancer, Kennedy’s disease, and male infertility. Mutations in the AR gene can cause complete androgen insensitivity (CAIS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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