Thermo Fisher Scientific 5HT2C Receptor Polyclonal Antibody
5HT2C 수용체를 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ELISA, IP 등 다양한 응용에 적합. 인간, 마우스, 설치류 등 반응성 보유. 고순도 친화 크로마토그래피 정제, 안정적 액상 형태로 연구용에 최적화.
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Thermo Fisher Scientific 5HT2C Receptor Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 400–458 of human 5-hydroxytryptamine receptor 2C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter that exerts diverse physiological effects through several receptor subtypes, including the 5-HT2 family of G-protein-coupled receptors. These receptors activate phospholipase C and D signaling pathways. The 5HT2C receptor gene undergoes multiple RNA editing events, converting adenosine residues to inosines, which can alter amino acids within the receptor’s intracellular loop. This editing generates receptor isoforms with different G-protein interaction capabilities and signaling responses, influencing serotonergic neurotransmission in the central nervous system. Abnormal 5-HT2C editing patterns have been observed in depressed suicide victims.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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