Thermo Fisher Scientific TIP60 Monoclonal Antibody (3F9)
TIP60 단백질을 인식하는 Mouse monoclonal antibody (clone 3F9). Western blot, IHC(P), ELISA에 사용 가능. Human 시료에 반응하며, DNA 수선 및 전사 조절 연구에 적합. 4°C 단기 보관, -20°C 장기 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3F9 |
| Immunogen | Purified recombinant fragment of human TIP60 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10982514 |
Product Specific Information
MA5-15346 targets TIP60 in indirect ELISA, IHC, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human TIP60 expressed in E. coli.
MA5-15346 detects TIP60, which has a predicted molecular weight of approximately 60 kDa.
Target Information
TIP60 is a transcription factor originally isolated as an HIV-1 TAT-interactive protein. It interacts with the viral TAT protein, leading to HTATIP polyubiquitination and degradation.
Belonging to the MYST family of histone acetyltransferases (HATs), TIP60 is a catalytic subunit of the NuA4 complex involved in transcriptional activation through acetylation of nucleosomal histones H4 and H2A.
As a co-regulator of transcription factors, TIP60 can either promote or suppress tumorigenesis. It plays roles in DNA repair, apoptosis, and signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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